
Saffron (Crocus sativus) - red gold
- Saffron (Crocus sativus L.) is a plant from the iris family (Iridaceae). Only the dried stigmas of the flower are used - up to 150,000 flowers are harvested by hand for 1 kg of saffron.
- Its characteristic constituents are the carotenoids crocin and crocetin as well as the aroma compounds safranal and picrocrocin - combined in the Affron® extract as Lepticrosalides®.
- Saffron was already traded as the world's most precious spice in the ancient Mediterranean and the Near East - today the labour-intensive hand harvest makes it more expensive than some precious metals.
Affron® - a standardised branded extract instead of anonymous powder
- Green Naturals Saffron Capsules contain the patented branded extract Affron® at 30 mg per daily dose - compared to many manufacturers that use unstandardised saffron powder without defined active contents.
- Every batch is standardised to 3.5% Lepticrosalides® (1.05 mg per daily dose) - compared to many suppliers that do not declare any bioactive lead compounds.
- Affron® is the best-documented saffron extract: in one of the most recently published randomised, placebo-controlled 12-week studies of 86 women aged 50 to 70, the extract was investigated at 28 mg per day (Lopresti & Smith, 2026) - and the bioaccessibility of its lead compounds has been confirmed pharmacokinetically (Almodóvar et al., 2020).
Plus vitamins B1 & B3 - with substantiated benefits
- Vitamin B1 (thiamine) and niacin (vitamin B3) contribute to normal psychological function, normal functioning of the nervous system and normal energy-yielding metabolism - niacin additionally contributes to the reduction of tiredness and fatigue (authorised EFSA claims).
- Both vitamins are dosed at exactly 100% of the Nutrient Reference Value (NRV): 1.1 mg vitamin B1 and 16 mg niacin (NE) per daily dose - sensibly supplemented instead of overdosed.
- 150 vegan capsules per bottle last for 75 days - a convenient 2.5-month supply at 2 capsules daily.
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Optimal time of intake
Take 2 capsules daily with sufficient water, ideally in the morning with a meal. The time of intake can be chosen individually - what matters is regular daily intake.
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Dosage and duration of use
Daily dose: 2 capsules (= 30 mg Affron® saffron extract with 1.05 mg Lepticrosalides®, 16 mg niacin and 1.1 mg vitamin B1). We recommend continuous intake for at least 8 weeks. The pack of 150 capsules lasts for 75 days. Do not take during pregnancy; if you are taking antidepressants, please consult your doctor or pharmacist.
| Quality criterion | Green Naturals® | Other manufacturers |
|---|---|---|
| Raw material & standardisation | ✔ branded extract Affron®, standardised to 3.5% Lepticrosalides® (1.05 mg/day) | ✕ |
| Clinical documentation | ✔ extract investigated in RCTs, incl. pharmacokinetics | ✕ |
| Sensible dosage | ✔ 30 mg per daily dose, study-based | ✕ |
| Purity & authenticity | ✔ every batch independently lab-tested | ✕ |
| Substantiated benefit (EFSA) | ✔ B1 + B3 with authorised claims (psyche, nervous system, fatigue) | ✕ |
| Formula & tolerability | ✔ vegan HPMC capsule, no unnecessary additives | ✕ |
| Transparency & responsibility | ✔ clear advice on pregnancy & antidepressants | ✕ |
| Practicality | ✔ 2 capsules daily, 150 capsules = 75 days | ✕ |
Our vision at Green Label® is to create products based on purity and transparency. Our approach is to source high-quality raw materials directly from leading producers worldwide to offer a product that is uncompromisingly committed to natural ingredients. Every capsule of our products carries the promise of purity, sustainability, and maximum effectiveness:
- Premium active ingredients as pure substances, directly from leading producers.
- Production and bottling under the highest pharmaceutical standards (GMP, ISO 22000:2018, HACCP).
- Maximum avoidance of all additives; only valuable natural substances are used.
- Vegan capsule shells, 100% free of PEG and other undesirable substances.
- Packaging in environmentally friendly, non-toxic materials for optimal aroma protection.
My name is Dr. Hari Sven Krishnan, founder of Heilpflanzenwohl GmbH and chief pharmacist.
Together with an experienced team of specialists, including Stephan Walz (pharmacist), Marie Schröder (nutritional scientist), and Dr. Christiane Gras (immunologist), we developed Green Naturals.
The result of intensive research with a clear goal: to offer you natural, highly effective products. At Heilpflanzenwohl, quality and purity come first, because we are convinced: "The best medicine comes from nature – we just need to learn how to use it correctly."
| Ingredients | 2 capsules/day | *NRV% |
|---|---|---|
| Niacin (Vitamin B3) | 16 mg NE | 100 % |
| Vitamin B1 | 1,1 mg | 100 % |
| Saffron dry extract | 30 mg | ** |
| • of which Lepticrosalides® | 1,05 mg | ** |
** no reference available
What is saffron?
Why is saffron so expensive?
Where does saffron come from?
Which plant is saffron obtained from?
What does saffron do in the body?
Is saffron healthy?
What is saffron extract (Affron®)?
What is the dosage of the saffron capsules?
Can the capsules be opened?
Is the product completely natural?
Is the product suitable for pregnant women?
Are the saffron capsules available in pharmacies?
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Sources
- Lopresti, A.L. & Smith, S.J. (2026). The effects of a saffron extract (Affron®) in women aged 50 to 70 years: a randomised, double-blind, placebo-controlled trial. Frontiers in Nutrition, 13, 1838513. DOI: 10.3389/fnut.2026.1838513
- Almodóvar, P. et al. (2020). Bioaccessibility and Pharmacokinetics of a Commercial Saffron (Crocus sativus L.) Extract. Evidence-Based Complementary and Alternative Medicine, 2020, 1575730. DOI: 10.1155/2020/1575730
- Cerdá-Bernad, D. et al. (2022). Saffron bioactives crocin, crocetin and safranal: effect on oxidative stress and mechanisms of action. Critical Reviews in Food Science and Nutrition, 62(12), 3232-3249. DOI: 10.1080/10408398.2020.1864279
- Jackson, P.A. et al. (2020). Effects of Saffron Extract Supplementation on Mood and Well-Being in Healthy Adults. Nutrients, 12(8), 2447. DOI: 10.3390/nu12082447
Remarks
- HACCP (Hazard Analysis and Critical Control Points) is a preventive system for ensuring food safety that identifies and assesses potential hazards in production and minimizes them through targeted control measures. The seal refers to the manufacturing process.
- This is how the grade is calculated: Grade calculation based on star ratings: 5.00 - 4.50 Very good, 4.49 - 3.50 Good, 3.49 - 2.50 Satisfactory, 2.49 - 1.50 Sufficient, 1.49 - 1.00 Poor. For the verification of ratings, no authenticity check of customer reviews is carried out. The ratings are combined from different sources, such as mail-order pharmacies and online marketplaces. Last updated: 13.10.26